Bloodstream infections initiated by ESBL-producing Escherichia coli in neonates and infants at two hospitals in Yaoundé, Cameroon

Early diagnosis and probabilistic antibiotic therapy based on known bacterial ecology sensibility can reduce mortality morbidity in pathologies caused by a infection. This study aimed at determining the prevalence risk factors of extended-spectrum β-lactamases (ESBLs)-producing Escherichia coli isolated from blood cultures neonates infants population. We conducted cross-sectional during which pathogenic bloodstream isolates were identified. Antibiotic susceptibility test was performed phenotypic confirmation ESBL production double-disc synergy test. Over course this study, 298 129 (43.3%) positive obtained. Of isolates, 90 (69.7%) 39 (30.2%) other bacteria strains that included Klebsiella oxytoca, Streptococcus pneumonia, Coagulase-negative staphylococci. indicated resistant to cephalosporin, penicillin, sulfonamide, aminoglycoside families. Further analysis 31 (34.4%) producers for infection ESBL-producing prior exposure antibiotics immune system depression. These findings clearly extend our understanding type initiated neonates, also provides useful information guide establishment an efficient therapeutic strategy community- hospital-acquired